[PDF][PDF] Changes in the ceramide profile of atopic dermatitis patients
J Ishikawa, H Narita, N Kondo, M Hotta… - Journal of Investigative …, 2010 - core.ac.uk
J Ishikawa, H Narita, N Kondo, M Hotta, Y Takagi, Y Masukawa, T Kitahara, Y Takema…
Journal of Investigative Dermatology, 2010•core.ac.ukWe wish to report the characteristic differences that have been identified between the
ceramide (CER) profiles of atopic dermatitis (AD) patients and those of healthy individuals.
AD is characterized by impaired stratum corneum (SC) functions, which can be indicated by
either an increase in transepidermal water loss (TEWL) or a decrease in water-holding
function (capacitance). On the other hand, a close relationship between the impaired SC
functions and CERs has been reported (Elias, 1983; Melnik et al., 1988; Yamamoto et al …
ceramide (CER) profiles of atopic dermatitis (AD) patients and those of healthy individuals.
AD is characterized by impaired stratum corneum (SC) functions, which can be indicated by
either an increase in transepidermal water loss (TEWL) or a decrease in water-holding
function (capacitance). On the other hand, a close relationship between the impaired SC
functions and CERs has been reported (Elias, 1983; Melnik et al., 1988; Yamamoto et al …
We wish to report the characteristic differences that have been identified between the ceramide (CER) profiles of atopic dermatitis (AD) patients and those of healthy individuals. AD is characterized by impaired stratum corneum (SC) functions, which can be indicated by either an increase in transepidermal water loss (TEWL) or a decrease in water-holding function (capacitance). On the other hand, a close relationship between the impaired SC functions and CERs has been reported (Elias, 1983; Melnik et al., 1988; Yamamoto et al., 1991; Motta et al., 1993, Paige et al., 1994; Di Nardo et al., 1998; Matsumoto et al.,
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