Clinical, immunologic and genetic profiles of DOCK8-deficient patients in Kuwait
W Al-Herz, R Ragupathy, MJ Massaad, A Nanda… - Clinical …, 2012 - Elsevier
Deficiency of dedicator of cytokinesis 8 (DOCK8) is a newly described combined primary
immunodeficiency disease. It was found to account for 15% of combined immune deficiency
cases in the National Primary Immunodeficiency Disorders Registry in Kuwait, a country with
high prevalence of consanguinity. We present the clinical, immunologic and molecular
characteristics of 9 Kuwaiti patients with DOCK8 deficiency and discuss differences that
distinguish DOCK8 deficiency from atopic dermatitis. Clinical immunologists in areas with …
immunodeficiency disease. It was found to account for 15% of combined immune deficiency
cases in the National Primary Immunodeficiency Disorders Registry in Kuwait, a country with
high prevalence of consanguinity. We present the clinical, immunologic and molecular
characteristics of 9 Kuwaiti patients with DOCK8 deficiency and discuss differences that
distinguish DOCK8 deficiency from atopic dermatitis. Clinical immunologists in areas with …
