The pathogenesis of vascular calcification in the chronic kidney disease mineral bone disorder: the links between bone and the vasculature
KA Hruska, S Mathew, RJ Lund, I Memon… - Seminars in nephrology, 2009 - Elsevier
Considerable scientific progress in the pathogenesis of vascular calcification that has
accrued in recent years is reviewed in this article. Factors regulating mesenchymal cell
differentiation and their role in the neointimal calcification of atherosclerosis and the
vascular media calcification observed in chronic kidney disease and diabetes are
discussed, as is the role of bone regulatory proteins in bone mineralization and vascular
calcification. This includes recent studies related to fetuin-A, and the discovery of a new …
accrued in recent years is reviewed in this article. Factors regulating mesenchymal cell
differentiation and their role in the neointimal calcification of atherosclerosis and the
vascular media calcification observed in chronic kidney disease and diabetes are
discussed, as is the role of bone regulatory proteins in bone mineralization and vascular
calcification. This includes recent studies related to fetuin-A, and the discovery of a new …
