Methods to detect NF-κB activity in tumor-associated macrophage (TAM) populations
F Sun, Z Qu, G Xiao - NF-κB Transcription Factors: Methods and Protocols, 2021 - Springer
F Sun, Z Qu, G Xiao
NF-κB Transcription Factors: Methods and Protocols, 2021•SpringerMacrophages are an abundant population in the tumor-infiltrating immune cells. The
transcription factor NF-κB plays an important role in the response of tumor-associated
macrophages (TAMs) to the tumor environmental cues. Detecting NF-κB activity in TAMs will
help define the functional status of the TAMs. In this article, we describe several methods to
detect NF-κB activity in TAM populations.
transcription factor NF-κB plays an important role in the response of tumor-associated
macrophages (TAMs) to the tumor environmental cues. Detecting NF-κB activity in TAMs will
help define the functional status of the TAMs. In this article, we describe several methods to
detect NF-κB activity in TAM populations.
Abstract
Macrophages are an abundant population in the tumor-infiltrating immune cells. The transcription factor NF-κB plays an important role in the response of tumor-associated macrophages (TAMs) to the tumor environmental cues. Detecting NF-κB activity in TAMs will help define the functional status of the TAMs. In this article, we describe several methods to detect NF-κB activity in TAM populations.
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