Longitudinal and simultaneous profiling of 11 modes of cell death in mouse retina post-optic nerve injury
Retinal ganglion cell (RGC) death is a critical pathological trigger leading to irreversible
visual impairment and blindness after optic nerve (ON) injury. Yet, there is still no effective
clinical treatment to rescue RGC death after ON injury. Understanding the involvement of
different modes of cell death post-ON injury could facilitate the development of targeting
treatments against RGC death. Herein we aimed to characterize the regulation of 11 modes
of cell death simultaneously and longitudinally in mouse retina post-ON injury. The number …
visual impairment and blindness after optic nerve (ON) injury. Yet, there is still no effective
clinical treatment to rescue RGC death after ON injury. Understanding the involvement of
different modes of cell death post-ON injury could facilitate the development of targeting
treatments against RGC death. Herein we aimed to characterize the regulation of 11 modes
of cell death simultaneously and longitudinally in mouse retina post-ON injury. The number …