Clinical course of hypertrophic cardiomyopathy in a regional United States cohort

BJ Maron, SA Casey, LC Poliac, TE Gohman… - Jama, 1999 - jamanetwork.com
ContextHypertrophic cardiomyopathy (HCM) has been regarded as a disease that causes
substantial disability, with annual mortality rates of up to 6%, based largely on reports from
tertiary referral centers. ObjectiveTo assess the clinical course of HCM in a patient cohort
more closely resembling the true disease state. DesignRetrospective cohort study. SettingA
regional cohort from Minnesota and adjoining regions, free of referral center bias, studied at
Minneapolis Heart Institute. PatientsTwo hundred seventy-seven consecutively studied HCM …