Alzheimer's disease (AD) involves amyloid β (Aβ) accumulation, oxidative damage, and
inflammation, and risk is reduced with increased antioxidant and anti-inflammatory
consumption. The phenolic yellow curry pigment curcumin has potent anti-inflammatory and
antioxidant activities and can suppress oxidative damage, inflammation, cognitive deficits,
and amyloid accumulation. Since the molecular structure of curcumin suggested potential
Aβ binding, we investigated whether its efficacy in AD models could be explained by effects …