Effects of prior osteoporosis treatment on 12-month treatment response of romosozumab in patients with postmenopausal osteoporosis
K Ebina, H Tsuboi, Y Nagayama, M Kashii… - Joint Bone Spine, 2021 - Elsevier
Objectives To investigate the effects of prior treatment and determine the predictors of a 12-
month treatment response of romosozumab (ROMO) in 148 patients with postmenopausal
osteoporosis. Methods In this prospective, observational, and multicenter study, treatment
naïve patients (Naïve; n= 50) or patients previously treated with bisphosphonates (BP; n=
37) or denosumab (DMAb; n= 45) or teriparatide (TPTD; n= 16)(mean age, 75.0 years; T-
scores of the lumbar spine [LS]− 3.2 and total hip [TH]− 2.6) were switched to ROMO due to …
month treatment response of romosozumab (ROMO) in 148 patients with postmenopausal
osteoporosis. Methods In this prospective, observational, and multicenter study, treatment
naïve patients (Naïve; n= 50) or patients previously treated with bisphosphonates (BP; n=
37) or denosumab (DMAb; n= 45) or teriparatide (TPTD; n= 16)(mean age, 75.0 years; T-
scores of the lumbar spine [LS]− 3.2 and total hip [TH]− 2.6) were switched to ROMO due to …
