Tolerogenic dendritic cells as a therapy for treating lupus

C Llanos, JP Mackern-Oberti, F Vega, SH Jacobelli… - Clinical …, 2013 - Elsevier
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that is characterized
by the over production of auto-antibodies against nuclear components. Thus, SLE patients
have increased morbidity and, mortality compared to healthy individuals. Available therapies
are not curative and are associated with unwanted adverse effects. During the last few
years, important advances in immunology research have provided rheumatologists with new
tools for designing novel therapies for treating autoimmunity. However, the complex nature …