[HTML][HTML] Altered metabolism of gut microbiota contributes to chronic immune activation in HIV-infected individuals

JF Vázquez-Castellanos, S Serrano-Villar, A Latorre… - Mucosal …, 2015 - Elsevier
Altered interplay between gut mucosa and microbiota during treated HIV infection may
possibly contribute to increased bacterial translocation and chronic immune activation, both
of which are predictors of morbidity and mortality. Although a dysbiotic gut microbiota has
recently been reported in HIV+ individuals, the metagenome gene pool associated with HIV
infection remains unknown. The aim of this study is to characterize the functional gene
content of gut microbiota in HIV+ patients and to define the metabolic pathways of this …