Effects of the modern food environment on striatal function, cognition and regulation of ingestive behavior

MV Burke, DM Small - Current opinion in behavioral sciences, 2016 - Elsevier
Highlights•Striatal circuits involved in associative learning are altered in obesity.•Differences
in neural reactivity to food cues and reward confer risk for overeating.•Excess intake of
dietary fat and sugar alters striatal dopamine function.•Diet-induced adaptations lead to
cognitive impairments that may potentiate risk.Emerging evidence from human and animal
studies suggest that consumption of palatable foods rich in fat and/or carbohydrates may
produce deleterious influences on brain function independently of body weight or metabolic …