LncRNA: a potential research direction in intestinal barrier function
ZF Jiang, L Zhang - Digestive Diseases and Sciences, 2021 - Springer
ZF Jiang, L Zhang
Digestive Diseases and Sciences, 2021•SpringerLong non-coding RNAs (lncRNAs) are transcripts longer than 200 nucleotides and play
important roles in a variety of diseases. LncRNAs are involved in many biologic processes
including cell differentiation, development, and apoptosis. The intestinal barrier is
considered one of the most important protective barriers in humans. Severe damage or
dysfunction of the intestinal barrier may be associated with the occurrence and development
of many diseases, such as inflammatory bowel disease and ulcerative colitis. LncRNAs have …
important roles in a variety of diseases. LncRNAs are involved in many biologic processes
including cell differentiation, development, and apoptosis. The intestinal barrier is
considered one of the most important protective barriers in humans. Severe damage or
dysfunction of the intestinal barrier may be associated with the occurrence and development
of many diseases, such as inflammatory bowel disease and ulcerative colitis. LncRNAs have …
Abstract
Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nucleotides and play important roles in a variety of diseases. LncRNAs are involved in many biologic processes including cell differentiation, development, and apoptosis. The intestinal barrier is considered one of the most important protective barriers in humans. Severe damage or dysfunction of the intestinal barrier may be associated with the occurrence and development of many diseases, such as inflammatory bowel disease and ulcerative colitis. LncRNAs have been found to be associated with intestinal barrier function in some studies, which are at an early stage. In this review, we introduce the roles of LncRNAs in the intestinal barrier and investigate the possibility of lncRNAs as a research field in the intestinal barrier.
Springer
