Extracellular vesicles as messengers between hepatocytes and macrophages in nonalcoholic steatohepatitis
JM Schattenberg, MS Lee - Gastroenterology, 2016 - gastrojournal.org
States, and major regions of Asia. The continuous increase of the underlying metabolic risk
factors, including abdominal adiposity, insulin resistance/diabetes, and hyperlipidemia has
put large populations at risk to develop advanced liver disease characterized by fibrosis or
even cirrhosis. 1 Although chronic viral hepatitis was the leading cause of hepatocellular
carcinoma for a long time, currently NASH is becoming an increasingly important cause of
end-stage liver disease. 2 In the clinical context, this has led to a strong increase in the …
factors, including abdominal adiposity, insulin resistance/diabetes, and hyperlipidemia has
put large populations at risk to develop advanced liver disease characterized by fibrosis or
even cirrhosis. 1 Although chronic viral hepatitis was the leading cause of hepatocellular
carcinoma for a long time, currently NASH is becoming an increasingly important cause of
end-stage liver disease. 2 In the clinical context, this has led to a strong increase in the …