The evaluation and treatment of Paget's disease of bone
FR Singer - Best Practice & Research Clinical Rheumatology, 2020 - Elsevier
Paget's disease of bone is a localized skeletal disorder, which is more common in England
and in countries to which the English migrated. In recent decades, the prevalence in most
countries has decreased. A family history of the disorder is present in approximately 15% of
patients. Patients may be asymptomatic and may be diagnosed accidently as a
consequence of an elevated serum alkaline phosphatase level or a finding on an x-ray or
nuclear bone scan. The diagnosis is made by x-ray but nuclear bone scans define the extent …
and in countries to which the English migrated. In recent decades, the prevalence in most
countries has decreased. A family history of the disorder is present in approximately 15% of
patients. Patients may be asymptomatic and may be diagnosed accidently as a
consequence of an elevated serum alkaline phosphatase level or a finding on an x-ray or
nuclear bone scan. The diagnosis is made by x-ray but nuclear bone scans define the extent …
