The CC chemokine receptor 6 (CCR6) is crucial for Th2-driven allergic conjunctivitis
SH Chung, SY Chang, HJ Lee, SH Choi - Clinical Immunology, 2015 - Elsevier
Allergic conjunctivitis from an allergen-driven Th2 response is characterized by conjunctival
eosinophilic infiltration. Although CCL20–CCR6 axis has been reported to play a
proinflammatory role in several murine models of autoimmune diseases including allergic
diseases, their underlying mechanism needs to be investigated. We here examined whether
CCL20–CCR6 axis could play a role in the development of allergic conjunctival
inflammation using murine experimental allergic conjunctivitis (EAC) model induced by …
eosinophilic infiltration. Although CCL20–CCR6 axis has been reported to play a
proinflammatory role in several murine models of autoimmune diseases including allergic
diseases, their underlying mechanism needs to be investigated. We here examined whether
CCL20–CCR6 axis could play a role in the development of allergic conjunctival
inflammation using murine experimental allergic conjunctivitis (EAC) model induced by …