Retinal vascular patterns: IV. Diabetic retinopathy

DG Cogan, D Toussaint… - Archives of ophthalmology, 1961 - jamanetwork.com
It is generally held that microaneurysms constitute the characteristic lesion of diabetic
retinopathy. First observed by MacKenzie and Nettleship in 1879, 1 the microaneurysms
were rediscovered by Ballantyne and Loewenstein in 1943 2 and have been described by
numerous clinicians and pathologists since that time. Noteworthy has been the predominant
localization of the diabetic microaneurysms in the central and paracentral regions, their
random distribution, and their association with punctate hemorrhages and" exudates" in the …