[HTML][HTML] NAFLD: a multisystem disease
CD Byrne, G Targher - Journal of hepatology, 2015 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
in Western countries that is predicted to become also the most frequent indication for liver
transplantation by 2030. Over the last decade, it has been shown that the clinical burden of
NAFLD is not only confined to liver-related morbidity and mortality, but there is now growing
evidence that NAFLD is a multisystem disease, affecting extra-hepatic organs and regulatory
pathways. For example, NAFLD increases risk of type 2 diabetes mellitus (T2DM) …
in Western countries that is predicted to become also the most frequent indication for liver
transplantation by 2030. Over the last decade, it has been shown that the clinical burden of
NAFLD is not only confined to liver-related morbidity and mortality, but there is now growing
evidence that NAFLD is a multisystem disease, affecting extra-hepatic organs and regulatory
pathways. For example, NAFLD increases risk of type 2 diabetes mellitus (T2DM) …