The RNA-binding protein RBM47 inhibits non-small cell lung carcinoma metastasis through modulation of AXIN1 mRNA stability and Wnt/β-catentin signaling
D Shen, Y Jiang, J Li, L Xu, K Tao - Surgical Oncology, 2020 - Elsevier
Background Non-small-cell lung cancer (NSCLC) remains a highly prevalent and deadly
form of cancer, with efforts to better understand the molecular basis of the progression of this
disease being essential to its effective treatment. Several recent studies have highlighted the
ability of RNA-binding proteins (RBPs) to regulate a wide range of cellular processes in both
healthy and pathogenic contexts. Among these RBPs, RNA binding motif protein 47
(RBM47) has recently been identified as a tumor suppressor in both breast and colon …
form of cancer, with efforts to better understand the molecular basis of the progression of this
disease being essential to its effective treatment. Several recent studies have highlighted the
ability of RNA-binding proteins (RBPs) to regulate a wide range of cellular processes in both
healthy and pathogenic contexts. Among these RBPs, RNA binding motif protein 47
(RBM47) has recently been identified as a tumor suppressor in both breast and colon …
