[HTML][HTML] A compact quadrupole-orbitrap mass spectrometer with FAIMS interface improves proteome coverage in short LC gradients
DB Bekker-Jensen, A Martínez-Val… - Molecular & Cellular …, 2020 - ASBMB
State-of-the-art proteomics-grade mass spectrometers can measure peptide precursors and
their fragments with ppm mass accuracy at sequencing speeds of tens of peptides per
second with attomolar sensitivity. Here we describe a compact and robust quadrupole-
orbitrap mass spectrometer equipped with a front-end High Field Asymmetric Waveform Ion
Mobility Spectrometry (FAIMS) Interface. The performance of the Orbitrap Exploris 480 mass
spectrometer is evaluated in data-dependent acquisition (DDA) and data-independent …
their fragments with ppm mass accuracy at sequencing speeds of tens of peptides per
second with attomolar sensitivity. Here we describe a compact and robust quadrupole-
orbitrap mass spectrometer equipped with a front-end High Field Asymmetric Waveform Ion
Mobility Spectrometry (FAIMS) Interface. The performance of the Orbitrap Exploris 480 mass
spectrometer is evaluated in data-dependent acquisition (DDA) and data-independent …
