Beneficial effect of cholestyramine in sclerosing cholangitis

DE Polter, V Gruhl, EH Eigenbrodt, B Combes - Gastroenterology, 1980 - Elsevier
DE Polter, V Gruhl, EH Eigenbrodt, B Combes
Gastroenterology, 1980Elsevier
Cholestyramine exerted a beneficial effect on the course of a patient with sclerosing
cholangitis associated with ulcerative proctitis. Over a 6.5-yr period, discontinuation of
Cholestyramine resulted in episodes of RUQ pain and/or appearance of abnormalities in
liver tests. Readministration of the resin was followed by disappearance of symptoms and
normalization of test results. The mechanism of the beneficial effect of Cholestyramine was
not elucidated.
Abstract
Cholestyramine exerted a beneficial effect on the course of a patient with sclerosing cholangitis associated with ulcerative proctitis. Over a 6.5-yr period, discontinuation of Cholestyramine resulted in episodes of RUQ pain and/or appearance of abnormalities in liver tests. Readministration of the resin was followed by disappearance of symptoms and normalization of test results. The mechanism of the beneficial effect of Cholestyramine was not elucidated.
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