The influence of bile salt structure on self-association in aqueous solutions.
A Roda, AF Hofmann, KJ Mysels - Journal of Biological Chemistry, 1983 - ASBMB
The relationship between chemical structure and the concentration at which self-association
occurs in water or in 0.15 M Na+ ion was examined for more than 50 bile salts and bile salt
analogues varying in substituents on the steroid nucleus or in the structure of the side chain.
Nuclear substituents varied in type (alpha-or beta-hydroxy, or oxo group) and number (1, 2,
or 3); side chain structure varied in the nature of the ionic group (unconjugated, glycine-or
taurine-conjugated, or zwitterion) or length of the side chain (5-, 4-, or 3-carbon atoms). The …
occurs in water or in 0.15 M Na+ ion was examined for more than 50 bile salts and bile salt
analogues varying in substituents on the steroid nucleus or in the structure of the side chain.
Nuclear substituents varied in type (alpha-or beta-hydroxy, or oxo group) and number (1, 2,
or 3); side chain structure varied in the nature of the ionic group (unconjugated, glycine-or
taurine-conjugated, or zwitterion) or length of the side chain (5-, 4-, or 3-carbon atoms). The …
