[HTML][HTML] Keratinocyte growth factor/fibroblast growth factor-7-regulated cell migration and invasion through activation of NF-κB transcription factors
J Niu, Z Chang, B Peng, Q Xia, W Lu, P Huang… - Journal of biological …, 2007 - ASBMB
Keratinocyte growth factor (KGF)/fibroblast growth factor-7 (FGF-7) is a paracrine-and
epithelium-specific growth factor produced by cells of mesenchymal origin. It acts exclusively
through FGF-7 receptor (FGFR2/IIIb), which is expressed predominantly by epithelial cells,
but not by fibroblasts, suggesting that it might function as a paracrine mediator of
mesenchymal-epithelial interactions. KGF/FGF-7 plays an essential role in the growth of
epithelial cells and is frequently overexpressed in cancers of epithelial origin such as …
epithelium-specific growth factor produced by cells of mesenchymal origin. It acts exclusively
through FGF-7 receptor (FGFR2/IIIb), which is expressed predominantly by epithelial cells,
but not by fibroblasts, suggesting that it might function as a paracrine mediator of
mesenchymal-epithelial interactions. KGF/FGF-7 plays an essential role in the growth of
epithelial cells and is frequently overexpressed in cancers of epithelial origin such as …