Aquaporin 4 IgG serostatus and outcome in recurrent longitudinally extensive transverse myelitis
Y Jiao, JP Fryer, VA Lennon, A McKeon… - JAMA …, 2014 - jamanetwork.com
Importance Studies focused on recurrent longitudinally extensive transverse myelitis
(rLETM) are lacking. Objectives To determine the aquaporin 4 (AQP4) IgG detection rate
using recombinant human APQ4-based assays in sequential serum specimens collected
from patients with rLETM categorized as negative by first-generation tissue-based indirect
immunofluorescence (IIF) assay and to define the clinical characteristics and motor disability
outcomes in AQP4-IgG–positive rLETM. Design, Setting, and Participants A search of the …
(rLETM) are lacking. Objectives To determine the aquaporin 4 (AQP4) IgG detection rate
using recombinant human APQ4-based assays in sequential serum specimens collected
from patients with rLETM categorized as negative by first-generation tissue-based indirect
immunofluorescence (IIF) assay and to define the clinical characteristics and motor disability
outcomes in AQP4-IgG–positive rLETM. Design, Setting, and Participants A search of the …
