Extent and consequences of antibody formation against adalimumab in patients with psoriasis: one-year follow-up
SP Menting, PPM van Lümig, ACQ de Vries… - JAMA …, 2014 - jamanetwork.com
Importance In a previously reported cohort of 29 patients with plaque-type psoriasis followed
up for 24 weeks, clinically relevant antidrug antibody (ADA) to adalimumab was frequently
found. Long-term data were lacking. We now present the extension of this study: 80 patients
followed up for 1 year. Objectives To assess the extent of ADA and its clinical consequences
after 24 weeks of adalimumab treatment for psoriasis in a cohort of 80 patients. Design,
Setting, and Participants A multicenter cohort study, performed in the outpatient dermatology …
up for 24 weeks, clinically relevant antidrug antibody (ADA) to adalimumab was frequently
found. Long-term data were lacking. We now present the extension of this study: 80 patients
followed up for 1 year. Objectives To assess the extent of ADA and its clinical consequences
after 24 weeks of adalimumab treatment for psoriasis in a cohort of 80 patients. Design,
Setting, and Participants A multicenter cohort study, performed in the outpatient dermatology …
