Tubular lesions predict renal outcome in antineutrophil cytoplasmic antibody–associated glomerulonephritis after rituximab therapy

AE Berden, RB Jones, DD Erasmus… - Journal of the …, 2012 - journals.lww.com
Histopathological features in renal biopsies of patients with antineutrophil cytoplasmic
antibody–associated vasculitis have predictive value for renal outcome in patients who
receive standard treatment with cyclophosphamide and corticosteroids; however, whether
the same holds true for rituximab-treated patients is unknown. We describe associations
between renal histopathology and outcomes among patients treated with a rituximab-based
regimen in the Randomized Trial of Rituximab versus Cyclophosphamide in ANCA …