[HTML][HTML] Comprehensive analysis of transcript changes associated with allograft rejection: combining universal and selective features
We annotated the top transcripts associated with kidney transplant rejection by p-value,
either universal for all rejection or selective for T cell–mediated rejection (TCMR) or antibody-
mediated rejection (ABMR; ClinicalTrials. gov NCT01299168). We used eight class-
comparison algorithms to interrogate microarray results from 703 biopsies, 205 with
rejection. The positive comparators were all rejection, TCMR, or ABMR; the negative
comparators varied from normal biopsies to all nonrejecting biopsies, including other …
either universal for all rejection or selective for T cell–mediated rejection (TCMR) or antibody-
mediated rejection (ABMR; ClinicalTrials. gov NCT01299168). We used eight class-
comparison algorithms to interrogate microarray results from 703 biopsies, 205 with
rejection. The positive comparators were all rejection, TCMR, or ABMR; the negative
comparators varied from normal biopsies to all nonrejecting biopsies, including other …
