Neuropeptide Y is expressed in subpopulations of insulin-and non-insulin-producing islet cells in the rat after dexamethasone treatment: a combined …
U Myrsen, B Ahren, F Sundler - Regulatory peptides, 1995 - Elsevier
Neuropeptide Y (NPY) is known to occur in adrenergic and non-adrenergic nerves in rat
pancreatic islets. Analysis of islet extracts has revealed local NPY synthesis after
glucocorticoid treatment. The cellular localisation of NPY expression in rat islets following
dexamethasone treatment (2 mg/kg daily, for 12 days), was investigated by a combination of
immunocytochemistry (ICC) and in situ hybridisation (ISH). NPY-immunoreactive nerve
fibres were seen in pancreatic islets of both control and dexamethasone-treated rats. In the …
pancreatic islets. Analysis of islet extracts has revealed local NPY synthesis after
glucocorticoid treatment. The cellular localisation of NPY expression in rat islets following
dexamethasone treatment (2 mg/kg daily, for 12 days), was investigated by a combination of
immunocytochemistry (ICC) and in situ hybridisation (ISH). NPY-immunoreactive nerve
fibres were seen in pancreatic islets of both control and dexamethasone-treated rats. In the …