Surgical management of pancreatic neuroendocrine tumors

A Chiruvella, DA Kooby - Surgical Oncology Clinics, 2016 - surgonc.theclinics.com
Pancreatic neuroendocrine tumors (pancNETs) are uncommon tumors with an estimated
incidence of 1 to 1.5 per 100,000 and a prevalence of 35 per 100,000 in the United States.
They originate from the embryonic endodermal cells that give rise to the islets of
Langerhans. These cells are specialized cells that produce, store, and secrete peptides and
biogenic amines and were formerly known as the amine precursor uptake and
decarboxylation cells or APUD cells. 1 PancNETs comprise 2% to 4% of all pancreatic …