Inherited CARD9 deficiency in otherwise healthy children and adults with Candida species–induced meningoencephalitis, colitis, or both
F Lanternier, SA Mahdaviani, E Barbati… - Journal of Allergy and …, 2015 - Elsevier
Background Invasive infections of the central nervous system (CNS) or digestive tract
caused by commensal fungi of the genus Candida are rare and life-threatening. The known
risk factors include acquired and inherited immunodeficiencies, with patients often
displaying a history of multiple infections. Cases of meningoencephalitis, colitis, or both
caused by Candida species remain unexplained. Objective We studied 5 previously healthy
children and adults with unexplained invasive disease of the CNS, digestive tract, or both …
caused by commensal fungi of the genus Candida are rare and life-threatening. The known
risk factors include acquired and inherited immunodeficiencies, with patients often
displaying a history of multiple infections. Cases of meningoencephalitis, colitis, or both
caused by Candida species remain unexplained. Objective We studied 5 previously healthy
children and adults with unexplained invasive disease of the CNS, digestive tract, or both …