JAKs and STATs in immunity, immunodeficiency, and cancer

JJ O'Shea, SM Holland, LM Staudt - New England Journal of …, 2013 - Mass Medical Soc
JJ O'Shea, SM Holland, LM Staudt
New England Journal of Medicine, 2013Mass Medical Soc
JAKs and STATs in Immunity, Immunodeficiency, and Cancer | NEJM Skip to main content
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A large number of cytokines signal through the JAK–STAT pathway. Abnormal function of this pathway may lead to a variety of diseases. Targeting the defects in this signaling pathway has already led to treatment advances, and further advances are likely.
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