Neutrophil-lymphocyte ratio as a marker of progression from non-dysplastic Barrett's esophagus to esophageal adenocarcinoma: a cross-sectional retrospective study

VJ Campos, GS Mazzini, JF Juchem… - Journal of Gastrointestinal …, 2020 - Elsevier
Background Immune imbalance and inflammation have been suggested as key factors of
Barrett's esophagus (BE) pathway towards adenocarcinoma. The neutrophil-lymphocyte
ratio (NLR) indirectly reflects the relation between innate and adaptive immune systems and
has been studied in premalignant conditions as a biomarker for cancer diagnosis. Our aim
was to investigate if increasing values of NLR correlated with advancing stages of BE
progression to dysplasia and neoplasia. Methods We retrospectively analyzed data of …