Modulation of lysyl oxidase by dietary copper in rats
RB Rucker, N Romero-Chapman, T Wong, J Lee… - The Journal of …, 1996 - Elsevier
Lysyl oxidase levels were estimated in rat tissues using an enzyme-linked immunosorption
assay (ELISA) and a functional assay standardized against known amounts of purified lysyl
oxidase. High concentrations of lysyl oxidase (≥ 150 μg/g of tissue or packed cells) were
detected in connective tissues, such as tendon and skin. Values for aorta, kidney, lung and
liver ranged from 30 to 150 μg/g of tissue; values for skeletal muscle and diaphragm were<
30 μg/g tissue. Purified rat skin lysyl oxidase catalyzed the release of 50–100 Bq of tritium …
assay (ELISA) and a functional assay standardized against known amounts of purified lysyl
oxidase. High concentrations of lysyl oxidase (≥ 150 μg/g of tissue or packed cells) were
detected in connective tissues, such as tendon and skin. Values for aorta, kidney, lung and
liver ranged from 30 to 150 μg/g of tissue; values for skeletal muscle and diaphragm were<
30 μg/g tissue. Purified rat skin lysyl oxidase catalyzed the release of 50–100 Bq of tritium …