B-cell suppression of delayed hypersensitivity reactions
SI Katz, D Parker, JL Turk - Nature, 1974 - nature.com
SI Katz, D Parker, JL Turk
Nature, 1974•nature.comDURING certain normal immunisation schedules, suppressor cells are generated and act in
suppressing the expression of delayed hypersensitivity reactions1, 2. The suppression is
immunologically specific and is dependent on living cells. We have suggested that the
suppressor cells were B cells because they are depleted when 300 mg kg− 1
cyclophosphamide (CY) is given 3 d before sensitisation3–5.
suppressing the expression of delayed hypersensitivity reactions1, 2. The suppression is
immunologically specific and is dependent on living cells. We have suggested that the
suppressor cells were B cells because they are depleted when 300 mg kg− 1
cyclophosphamide (CY) is given 3 d before sensitisation3–5.
Abstract
DURING certain normal immunisation schedules, suppressor cells are generated and act in suppressing the expression of delayed hypersensitivity reactions1,2. The suppression is immunologically specific and is dependent on living cells. We have suggested that the suppressor cells were B cells because they are depleted when 300 mg kg−1 cyclophosphamide (CY) is given 3 d before sensitisation3–5.
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