Liver dysfunction as a predictor of outcomes in patients with advanced heart failure requiring ventricular assist device support: Use of the Model of End-stage Liver …

JA Yang, TS Kato, BP Shulman, H Takayama… - The Journal of Heart and …, 2012 - Elsevier
BACKGROUND: Liver dysfunction increases post-surgical morbidity and mortality. The
Model of End-stage Liver Disease (MELD) estimates liver function but can be inaccurate in
patients receiving oral anti-coagulation. We evaluated the effect of liver dysfunction on
outcomes after ventricular assist device (VAD) implantation and the dynamic changes in
liver dysfunction that occur during VAD support. METHODS: We retrospectively analyzed
255 patients (147 with pulsatile devices and 108 with continuous-flow devices) who …