Worldwide increase in the prevalence of metabolic syndrome and diabetes mellitus type 2
(DM2) during the past decades has converted them into a global epidemic disease. It is not
well understood how these metabolic disorders initiate, but an increase in food consumption
associated to low physical activity leads to increase in body weight and obesity. This in turn,
elevates circulating lipids and cytokines release by adipose tissue, give the organism a
chronic inflammation and potentiate insulin secretion, causing insulin resistance. Depending …