Microvascular injury after lung transplantation
MR Nicolls, JL Hsu, X Jiang - Current opinion in organ …, 2016 - journals.lww.com
MR Nicolls, JL Hsu, X Jiang
Current opinion in organ transplantation, 2016•journals.lww.comAirway microvascular injury is a feature of lung transplantation that limits short-term and long-
term organ health. Although some problems are attributable to a missing bronchial artery
circulation, another significant issue involves alloimmune-mediated injury to transplant
airway microvessels. For a variety of reasons, bronchial artery revascularization surgery at
the time of transplantation has not been widely adopted, and the current best hope for this
era may be new medical approaches that offer protection against immune-mediated …
term organ health. Although some problems are attributable to a missing bronchial artery
circulation, another significant issue involves alloimmune-mediated injury to transplant
airway microvessels. For a variety of reasons, bronchial artery revascularization surgery at
the time of transplantation has not been widely adopted, and the current best hope for this
era may be new medical approaches that offer protection against immune-mediated …
Summary
Airway microvascular injury is a feature of lung transplantation that limits short-term and long-term organ health. Although some problems are attributable to a missing bronchial artery circulation, another significant issue involves alloimmune-mediated injury to transplant airway microvessels. For a variety of reasons, bronchial artery revascularization surgery at the time of transplantation has not been widely adopted, and the current best hope for this era may be new medical approaches that offer protection against immune-mediated vascular injury or that promote microvascular repair.
Lippincott Williams & Wilkins