The causal effects of alcohol on lipoprotein subfraction and triglyceride levels using a Mendelian randomization analysis: The Nagahama study
Y Tabara, H Arai, Y Hirao, Y Takahashi, K Setoh… - Atherosclerosis, 2017 - Elsevier
Background Light-to-moderate alcohol consumption may increase circulating high-density
lipoprotein cholesterol (HDL-C) levels and decrease low-density lipoprotein cholesterol
(LDL-C) levels. However, the effect of alcohol on biologically important lipoprotein
subfractions remains largely unknown. Here we aimed to clarify the effects of alcohol on
lipoprotein subfractions using a Mendelian randomization analysis. Methods The study
subjects consisted of 8364 general Japanese individuals. The rs671 polymorphism in …
lipoprotein cholesterol (HDL-C) levels and decrease low-density lipoprotein cholesterol
(LDL-C) levels. However, the effect of alcohol on biologically important lipoprotein
subfractions remains largely unknown. Here we aimed to clarify the effects of alcohol on
lipoprotein subfractions using a Mendelian randomization analysis. Methods The study
subjects consisted of 8364 general Japanese individuals. The rs671 polymorphism in …