Association of HLA-A,-B, and-DRB1 with pulmonary tuberculosis in western Javanese Indonesia
R Yuliwulandari, Q Sachrowardi, H Nakajima… - Human immunology, 2010 - Elsevier
Genetic studies of pulmonary tuberculosis (PTB), including those of human leukocyte
antigen (HLA) genes, have been reported in several populations. Some studies also have
reported these genes to have a stronger role in severe tuberculosis. We investigated HLA
class I and II alleles and haplotypes to ascertain their role in susceptibility and resistance to
new and recurrent PTB in 257 PTB patients (216 new and 41 recurrent PTB patients) and
236 healthy controls in Western Javanese (Indonesia). HLA-B⁎ 4006 was associated with …
antigen (HLA) genes, have been reported in several populations. Some studies also have
reported these genes to have a stronger role in severe tuberculosis. We investigated HLA
class I and II alleles and haplotypes to ascertain their role in susceptibility and resistance to
new and recurrent PTB in 257 PTB patients (216 new and 41 recurrent PTB patients) and
236 healthy controls in Western Javanese (Indonesia). HLA-B⁎ 4006 was associated with …