Chemoablation of metastatic melanoma using intralesional Rose Bengal
JF Thompson, P Hersey, E Wachter - Melanoma research, 2008 - journals.lww.com
To study the effects of intralesional Rose Bengal for chemoablation of metastatic melanoma.
Twenty-six target lesions in 11 patients with locoregionally recurrent disease were injected
with the agent PV-10 (10% w/v Rose Bengal in saline) at a dose of 0.5 ml/cc lesion volume.
An additional 28 untreated lesions were observed for potential bystander effect. The
treatment was well tolerated and an objective response was observed in 12 target lesions,
with an additional seven lesions remaining static over at least 12 weeks of observation. In …
Twenty-six target lesions in 11 patients with locoregionally recurrent disease were injected
with the agent PV-10 (10% w/v Rose Bengal in saline) at a dose of 0.5 ml/cc lesion volume.
An additional 28 untreated lesions were observed for potential bystander effect. The
treatment was well tolerated and an objective response was observed in 12 target lesions,
with an additional seven lesions remaining static over at least 12 weeks of observation. In …
