Tetralogy of Fallot repair: ready for a new paradigm

T Geva - The Journal of Thoracic and Cardiovascular Surgery, 2012 - jtcvs.org
Since Alfred Blalock and Helen Taussig described the first surgical treatment option for
patients with tetralogy of Fallot (TOF) in 1945, the management of this once nearly uniformly
lethal disease has evolved considerably. As a consequence of seminal advances in
management made during the ensuing 6 decades, early surgical mortality has decreased
from 50% in the late 1950s to less than 2% in the modern surgical era. 1, 2 This remarkable
success story, however, is tempered by the realization that both past and current surgical …