Variant brain-derived neurotrophic factor (Valine66Methionine) polymorphism contributes to developmental and estrous stage-specific expression of anxiety-like …
BACKGROUND: Most anxiety and depressive disorders are twice as common in women
compared with men, and the sex difference in prevalence typically emerges during
adolescence. Hormonal changes across the menstrual cycle and during the postpartum and
perimenopausal periods are associated with increased risk for anxiety and depression
symptoms. In humans and animals, reduced brain-derived neurotrophic factor (BDNF) has
been associated with increased expression of affective pathology. Recently, a single …
compared with men, and the sex difference in prevalence typically emerges during
adolescence. Hormonal changes across the menstrual cycle and during the postpartum and
perimenopausal periods are associated with increased risk for anxiety and depression
symptoms. In humans and animals, reduced brain-derived neurotrophic factor (BDNF) has
been associated with increased expression of affective pathology. Recently, a single …
