Bleomycin-induced pulmonary toxicity
K Jules-Elysee, DA White - Clinics in chest medicine, 1990 - Elsevier
Bleomycin (BLM) is an antitumor antibiotic isolated from Streptomyces verticillus by
Umezawa and co-workers." It is active against a variety of tumors including squamous cell
carcinoma of the head and neck area, cervix, and esophagus, as well as germ cell tumors
and Hodgkin's and non-Hodgkin's lymphomas. 10, 13 Dosage of the drug, which consists of
the sulfate salt of a mixture of polypeptides, is often expressed in units rather than milligrams
to better reflect activity. BLM exerts its antineoplastic action through its ability to cause DNA …
Umezawa and co-workers." It is active against a variety of tumors including squamous cell
carcinoma of the head and neck area, cervix, and esophagus, as well as germ cell tumors
and Hodgkin's and non-Hodgkin's lymphomas. 10, 13 Dosage of the drug, which consists of
the sulfate salt of a mixture of polypeptides, is often expressed in units rather than milligrams
to better reflect activity. BLM exerts its antineoplastic action through its ability to cause DNA …
