Deciphering laminar-specific neural inputs with line-scanning fMRI
X Yu, C Qian, D Chen, SJ Dodd, AP Koretsky - Nature methods, 2014 - nature.com
X Yu, C Qian, D Chen, SJ Dodd, AP Koretsky
Nature methods, 2014•nature.comUsing a line-scanning method during functional magnetic resonance imaging (fMRI), we
obtained high temporal (50-ms) and spatial (50-μm) resolution information along the cortical
thickness and showed that the laminar position of fMRI onset coincides with distinct neural
inputs in rat somatosensory and motor cortices. This laminar-specific fMRI onset allowed us
to identify the neural inputs underlying ipsilateral fMRI activation in the barrel cortex due to
peripheral denervation-induced plasticity.
obtained high temporal (50-ms) and spatial (50-μm) resolution information along the cortical
thickness and showed that the laminar position of fMRI onset coincides with distinct neural
inputs in rat somatosensory and motor cortices. This laminar-specific fMRI onset allowed us
to identify the neural inputs underlying ipsilateral fMRI activation in the barrel cortex due to
peripheral denervation-induced plasticity.
Abstract
Using a line-scanning method during functional magnetic resonance imaging (fMRI), we obtained high temporal (50-ms) and spatial (50-μm) resolution information along the cortical thickness and showed that the laminar position of fMRI onset coincides with distinct neural inputs in rat somatosensory and motor cortices. This laminar-specific fMRI onset allowed us to identify the neural inputs underlying ipsilateral fMRI activation in the barrel cortex due to peripheral denervation-induced plasticity.
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