Multiple organ failure syndrome in the 1990s: systemic inflammatory response and organ dysfunction

AL Beal, FB Cerra - Jama, 1994 - jamanetwork.com
Objective.—This review of the systemic inflammatory response syndrome (SIRS) and
multiple organ dysfunction syndrome (MODS) provides an overview of a common but
complex problem found in critically ill patients. It emphasizes definitions, common clinical
patterns, metabolic responses, and pathophysiological changes. A brief discussion of
treatment concepts is also included. Data Sources.—Data for this review were gathered from
peer-reviewed journals, review articles by experts in SIRS/MODS, and selections from …