Fatty acid-binding protein 4 is associated with endothelial dysfunction in patients with type 2 diabetes
G Aragonès, R Ferré, I Lázaro, A Cabré, N Plana… - Atherosclerosis, 2010 - Elsevier
OBJECTIVE: Adipocyte fatty acid-binding protein (FABP4) plasma levels are higher in type 2
diabetes (T2D). Endothelial dysfunction is also common in T2D. We have investigated the
relationship between circulating FABP4 levels and endothelial function in diabetic patients.
METHODS: In 257 patients (105 diabetic and 152 non-diabetic) at increased risk of
cardiovascular disease, we measured circulating FABP4, reactive hyperemia index (RHI) by
peripheral artery tonometry, intima-media thickness, and biomarkers of inflammation …
diabetes (T2D). Endothelial dysfunction is also common in T2D. We have investigated the
relationship between circulating FABP4 levels and endothelial function in diabetic patients.
METHODS: In 257 patients (105 diabetic and 152 non-diabetic) at increased risk of
cardiovascular disease, we measured circulating FABP4, reactive hyperemia index (RHI) by
peripheral artery tonometry, intima-media thickness, and biomarkers of inflammation …
