[HTML][HTML] Postprandial recruitment of neutrophils may contribute to endothelial dysfunction
A Van Oostrom, TP Sijmonsma, C Verseyden… - Journal of lipid …, 2003 - ASBMB
Atherosclerosis is a low-grade inflammatory disease involving leukocytes, lipids, and
glucose leading to endothelial dysfunction. Since activation of neutrophils by triglycerides
and glucose has been described in vitro, we hypothesized that the postprandial phase is an
inflammatory state affecting leukocytes, possibly contributing to endothelial dysfunction. We
measured postprandial blood leukocyte counts, cytokines, hydroperoxides (HPOs), and flow-
mediated vasodilation (FMD) in eight healthy males (age 23±2 years) after a FAT (50 g/m 2) …
glucose leading to endothelial dysfunction. Since activation of neutrophils by triglycerides
and glucose has been described in vitro, we hypothesized that the postprandial phase is an
inflammatory state affecting leukocytes, possibly contributing to endothelial dysfunction. We
measured postprandial blood leukocyte counts, cytokines, hydroperoxides (HPOs), and flow-
mediated vasodilation (FMD) in eight healthy males (age 23±2 years) after a FAT (50 g/m 2) …