Background Autophagy plays an important role in causing inflammatory responses initiated
by environmental pollutants and respiratory tract infection. Objective We sought to
investigate the role of cockroach allergen–induced excessive activation of autophagy in
allergic airway inflammation and its underlying molecular mechanisms. Methods
Environmental allergen–induced autophagy was investigated in the primary human
bronchial epithelial cells (HBECs) and lung tissues of asthmatic mouse model and patients …