[HTML][HTML] Dysregulation of type 2 innate lymphoid cells and TH2 cells impairs pollutant-induced allergic airway responses
KC De Grove, S Provoost, RW Hendriks… - Journal of Allergy and …, 2017 - Elsevier
Background Although the prominent role of TH 2 cells in type 2 immune responses is well
established, the newly identified type 2 innate lymphoid cells (ILC2s) can also contribute to
orchestration of allergic responses. Several experimental and epidemiologic studies have
provided evidence that allergen-induced airway responses can be further enhanced on
exposure to environmental pollutants, such as diesel exhaust particles (DEPs). However, the
components and pathways responsible remain incompletely known. Objective We sought to …
established, the newly identified type 2 innate lymphoid cells (ILC2s) can also contribute to
orchestration of allergic responses. Several experimental and epidemiologic studies have
provided evidence that allergen-induced airway responses can be further enhanced on
exposure to environmental pollutants, such as diesel exhaust particles (DEPs). However, the
components and pathways responsible remain incompletely known. Objective We sought to …
