BACKGROUND: Mesenchymal stem cells (MSCs) show differentiation capacity along
mesenchymal lineages and have the potential to aid tissue regeneration. MSC
transplantation strategies are therefore currently being assessed following injury to various
organs. However, potential MSC migration to these organs after intravenous (IV) MSC
injection continues to be impeded by cell trapping within the lung. METHODS: Mouse MSCs
were isolated, purified, transfected with firefly luciferase, and labeled with CSFE. Their size …