Prognostic effect and longitudinal hemodynamic assessment of borderline pulmonary hypertension

TR Assad, BA Maron, IM Robbins, M Xu… - JAMA …, 2017 - jamanetwork.com
Importance Pulmonary hypertension (PH) is diagnosed by a mean pulmonary arterial
pressure (mPAP) value of at least 25 mm Hg during right heart catheterization (RHC). While
several studies have demonstrated increased mortality in patients with mPAP less than that
threshold, little is known about the natural history of borderline PH. Objective To test the
hypothesis that patients with borderline PH have decreased survival compared with patients
with lower mPAP and frequently develop overt PH and to identify clinical correlates of …